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Anti-BAX Polyclonal Antibody

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Cat.No：K110973P Solarbio

Reactivity：Rat,Human,Mouse

Application： IF,WB

Storage：Store at -20℃. Avoid freeze/thaw cycles.

Host：Rabbit

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Product Information

Name	Anti-BAX Polyclonal Antibody
Host	Rabbit
Clone Type	Polyclonal Antibody
Subtype	IgG
Predicted Reactivity	Bovine
Dilution Ratio	WB 1:1000-3000. IF 1:50-200.
Target	BAX
Background	Plays a role in the mitochondrial apoptotic process. Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Swiss Prot	Q07812
Gene ID	581
Subcellular Location	Cytoplasm Cell membrane
Immunogen	Recombinant protein of human BAX
Public Immunogen Range	1-192aa
Calculated MW	5/13/16/18/19/20/21/24kDa
Purification Method	Affinity purification
Storage Buffer	PBS with 50% Glycerol，0.03% Proclin300，0.5% BSA，pH 7.3.
Storage	Store at -20℃. Avoid freeze/thaw cycles.
Piece	Piece
Specification	50ul 100ul
Reactivity	Human Rat Mouse
Application	WB IF

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

Kindly reminder：Quick spin before use. If you have any questions, please contact us.

Note：

1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.

2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.

3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.