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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Trelagliptin SuccinateCAS：1029877-94-8
Molecular Formula：C22H26FN5O6
Molecular Weight：475.47
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1029877-94-8 |
| Name | Trelagliptin Succinate |
| Molecular Formula | C22H26FN5O6 |
| Molecular Weight | 475.47 |
| Solubility | Soluble in DMSO ≥5mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD22665720 |
| SMILES | CN1C(=O)C=C(N(C1=O)CC2=C(C=CC(=C2)F)C#N)N3CCC[C@H](C3)N.C(CC(=O)O)C(=O)O |
| Target Point | Dipeptidyl Peptidase（DPP-4） |
| Passage | Metabolic Enzyme&Protease |
| Background | It is a long-acting DPP-4 inhibitor. |
| Biological Activity | Trelagliptin (SYR-472) succinate is a potent， orally active and highly selective DPP-4 inhibitor with an IC50 of 4 nM. Trelagliptin succinate improves glycemic control in vivo and can be used for the study of type 2 diabetes mellitus (T2DM)[1]. |
| IC50 | IC50: 4nM(DPP-4)[1] |
| Data Literature Source | [1]. Bhumika D Patel，et al. Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors. Eur J Med Chem. 2014 Mar 3;74:574-605. |
| Unit | Bottle |
| Specification | 5mg 10mg 25mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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