{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Metabolic Enzyme & Protease > Camostat MesilateCAS：59721-29-8
Molecular Formula：C20H22N4O5·CH4O3S
Molecular Weight：494.52
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 59721-29-8 |
| Name | Camostat Mesilate |
| Molecular Formula | C20H22N4O5·CH4O3S |
| Molecular Weight | 494.52 |
| Solubility | Soluble in Water/DMSO |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| MDL | MFCD00941410 |
| SMILES | O=C(OCC(N(C)C)=O)CC1=CC=C(OC(C2=CC=C(NC(N)=N)C=C2)=O)C=C1.CS(=O)(O)=O |
| Target Point | Ser/Thr Protease，SARS-CoV |
| Passage | Anti-infection |
| Background | Camostat Mesilate is a potent trypsin-like protease inhibitor that acts by inhibiting airway epithelial sodium channel (ENaC) function. |
| Biological Activity | Camostat mesylate (Camostat mesilate) is an orally active, synthetic serine protease inhibitor for chronic pancreatitis. Camostat mesylate, an inhibitor of TMPRSS2, shows antiviral activity against SARS-CoV-2. Camostat mesylate also inhibits the activity of prostasin, trypsin, and matriptase[1-3]. |
| Data Literature Source | [1]. Gibo J，et al. Camostat mesilate attenuates pancreatic fibrosis via inhibition of monocytes and pancreatic stellate cells activity. Lab Invest. 2005;85(1):75‐89. [2]. Uno Y. Camostat mesilate therapy for COVID-19 [published online ahead of print，2020 Apr 29]. Intern Emerg Med. 2020;1‐2. [3]. Coote K，et al. Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease. J Pharmacol Exp Ther. 2009;329(2):764‐774. [4]. Zhou Y，Vedantham P，Lu K，et al. Protease inhibitors targeting coronavirus and filovirus entry. Antiviral Res. 2015;116:76‐84. |
| Unit | Bottle |
| Specification | 10mg 25mg 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
