Gene Name |
GBA3 |
English Name |
glucosidase, beta, acid 3 (cytosolic) |
Chinese Name |
胞浆β-葡萄糖苷酶 |
Uniprot |
Q9H227 |
GeneID |
57733 |
Predicted Cross Reactivity |
Human (Orangutan) |
氨基酸大小 |
18kDa |
表达氨基酸 |
1-163aa |
Background |
Neutral cytosolic beta-glycosidase with a broad substrate specificity that could play a role in the catabolism of glycosylceramides (PubMed:11389701, PubMed:11784319, PubMed:20728381, PubMed:26724485, PubMed:17595169).Has a significant glucosylceramidase activity in vitro (PubMed:26724485, PubMed:17595169).However, that activity is relatively low and its significance in vivo is not clear (PubMed:26724485, PubMed:17595169, PubMed:20728381).Also able to hydrolyze galactosylceramide/GalCer, glucosylsphingosine/GlcSph and galactosylsphingosine/GalSph (PubMed:17595169).However, the in vivo relevance of these activities is unclear (PubMed:17595169).It can also hydrolyze a broad variety of dietary glycosides including phytoestrogens, flavonols, flavones, flavanones and cyanogens in vitro and could therefore play a role in the metabolism of xenobiotics (PubMed:11784319).Could also play a role in the catabolism of cytosolic sialyl free N-glycans (PubMed:26193330). |
Application |
Immunology research |
Source |
E.coli |
Purification |
NI-NTA affinity purification |
Formulation |
Lyophilized from a 0.2 μm filtered solution of Urea, Tris-HCl, PH8.0. |
Delivery Condition |
The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage |
Reconstituted protein solution can be stored at 4-7°C for 2-3 months, stable at < -20°C for 1-2 years. |
Reconstitution |
Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity |
Purity≥85% as determined by reducing SDS-PAGE. |
Bioactive |
Not tested. |
Tag information |
With a 6His tag at the N-terminus. |
Unit |
Piece |
Specification |
10ug 50ug 100ug 1mg |