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Benzethonium Chloride

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Cat.No：IB1520 Solarbio

CAS：121-54-0

Molecular Formula：C₂₇H₄₂ClNO₂

Molecular Weight：448.08

Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：≥98%

Appearance：White to light yellow Solid

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Product Information

CAS	121-54-0
Name	Benzethonium Chloride
Molecular Formula	C₂₇H₄₂ClNO₂
Molecular Weight	448.08
Solubility	Soluble in Water/DMSO
Purity	≥98%
Appearance	White to light yellow Solid
Storage	Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 204-479-9
MDL	MFCD00011742
SMILES	CC(C)(C)CC(C)(C)C1=CC=C(C=C1)OCCOCC[N+](C)(C)CC2=CC=CC=C2.[Cl-]
InChIKey	UREZNYTWGJKWBI-UHFFFAOYSA-M
InChI	InChI=1S/C27H42NO2.ClH/c1-26(2,3)22-27(4,5)24-13-15-25(16-14-24)30-20-19-29-18-17-28(6,7)21-23-11-9-8-10-12-23;/h8-16H,17-22H2,1-7H3;1H/q+1;/p-1
PubChem CID	8478
Target Point	nAChR
Passage	Neuronal Signaling;Membrane Transporter&Ion Channel
Background	Benzethonium Chloride is a potent inhibitor of neuronal nicotinic acetylcholine receptors (nAChRs), inhibiting α4β2 nAChRs and α7 nAChRsM.
Biological Activity	Benzethonium chloride 是有效的neuronal nicotinic acetylcholine receptors (nAChRs)（神经元烟碱型乙酰胆碱受体）抑制剂，抑制α4β2 nAChRs和α7 nAChRs，IC50分别为49 nM 和 122 nM。[1]
Data Literature Source	[1] Coates KM，et al. Br J Pharmacol，2001，134(4)，871-879. [2] Yip KW，et al. Clin Cancer Res，2006，12(18)，5557-5569.
Unit	Bottle
Specification	100mg 250mg 500mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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