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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Neuronal Signal Pathway > BaclofenCAS：1134-47-0
Molecular Formula：C10H12ClNO2
Molecular Weight：213.66
Storage：Powder:-20℃，2 years
Purity：≥98%
Appearance：White to off-white Solid
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| CAS | 1134-47-0 |
| Name | Baclofen |
| Molecular Formula | C10H12ClNO2 |
| Molecular Weight | 213.66 |
| Solubility | Soluble in DMSO ＜ 1mg/mL |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years |
| EC | EINECS 214-486-9 |
| MDL | MFCD00055143 |
| SMILES | C1=CC(=CC=C1C(CC(=O)O)CN)Cl |
| InChIKey | KPYSYYIEGFHWSV-UHFFFAOYSA-N |
| InChI | InChI=1S/C10H12ClNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14) |
| PubChem CID | 2284 |
| Target Point | GABA Receptor |
| Passage | Neuronal Signaling;GPCR & G Protein |
| Background | Baclofen is a potent and selective metabotropic GABA-B receptor (GABABR) agonist. |
| Biological Activity | Baclofen是GABA衍生物，被用作骨骼肌的弛缓药和中枢神经系统抑制剂。它能够激活GABA receptors，尤其是GABAB受体。[2] |
| Data Literature Source | [1] Li Liu，et al. Scientific Reports. 2015，5: 14474. [2] Di Ciano P，et al. Neuropsychopharmacology. 2003，28(3):510-8. [3] Wang T，et al. Life Sci. 2008，82(9-10):536-41. |
| Unit | Bottle |
| Specification | 500mg 1g |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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