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7,8-Dihydroxyflavone

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Cat.No：ID1340 Solarbio

CAS：38183-03-8

Molecular Formula：C₁₅H₁₀O₄

Molecular Weight：254.24

Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year

Purity：HPLC≥98%

Appearance：Light yellow to green Solid

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Product Information

CAS	38183-03-8
Name	7,8-Dihydroxyflavone
Molecular Formula	C₁₅H₁₀O₄
Molecular Weight	254.24
Solubility	Soluble in DMSO ≥20mg/mL
Purity	HPLC≥98%
Appearance	Light yellow to green Solid
Storage	Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
EC	EINECS 253-812-4
MDL	MFCD00006836
SMILES	O=C1C=C(C2=CC=CC=C2)OC3=C(O)C(O)=CC=C13
InChIKey	COCYGNDCWFKTMF-UHFFFAOYSA-N
InChI	InChI=1S/C15H10O4/c16-11-7-6-10-12(17)8-13(19-15(10)14(11)18)9-4-2-1-3-5-9/h1-8,16,18H
PubChem CID	1880
Target Point	Trk Receptor
Passage	Protein Tyrosine Kinase/RTK;Neuronal Signaling
Background	7,8-Dihydroxyflavone is a potent and selective TrkB agonist.
Biological Activity	7,8-Dihydroxyflavone (7,8-DHF) 是有效的、选择性的TrkB受体激动剂（Kd≈320 nM）。TrkB受体是脑源性神经营养因子的主要信号受体。[1-3]
IC50	TrkB receptor:320nM(Kd) [1]
Data Literature Source	[1] Liu C，et al. Transl Neurodegener. 2016，5:2. [2] Bollen E，et al. Behav Brain Res. 2013，257:8-12. [3] Han XH，et al. Neurosci Lett. 2014，581:85-8.
Unit	Bottle
Specification	20mg 50mg 100mg

Remark：These protocols are for reference only. Solarbio does not independently validate these methods.

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