English Name |
Anti-ITLN1 Polyclonal Antibody |
Chinese Name |
内凝集素1抗体 |
Host |
Rabbit |
Clone Type |
Polyclonal Antibody |
Subtype |
IgG |
Dilution Ratio |
IHC 1:100-300. |
Target |
ITLN1 |
Synonyms |
Endothelial lectin HL 1, Endothelial lectin HL-1, Galactofuranose binding lectin, Galactofuranose-binding lectin, hIntL, HL 1, HL1, Intelectin, Intelectin 1, Intelectin-1, Intestinal lactoferrin receptor, INTL, ITLN, ITLN-1, ITLN1, ITLN1_HUMAN, LFR, Omentin |
Background |
Lectin that specifically recognizes microbial carbohydrate chains in a calcium-dependent manner. Binds to microbial glycans that contain a terminal acyclic 1,2-diol moiety, including beta-linked D-galactofuranose (beta-Galf), D-phosphoglycerol-modified glycans, D-glycero-D-talo-oct-2-ulosonic acid (KO) and 3-deoxy-D-manno-oct-2-ulosonic acid (KDO). Binds to glycans from Gram-positive and Gram-negative bacteria, including K.pneumoniae, S.pneumoniae, Y.pestis, P.mirabilis and P.vulgaris. Does not bind human glycans. Probably plays a role in the defense system against microorganisms (Probable). May function as adipokine that has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May interact with lactoferrin/LTF and increase its uptake, and may thereby play a role in iron absorption. |
Swiss Prot |
Q8WWA0 |
Gene ID |
55600 |
Subcellular Location |
Secreted Cell membrane |
Immunogen |
Recombinant protein of human ITLN1 |
Public Immunogen Range |
1-314aa |
Calculated MW |
35kDa |
Purification Method |
Affinity purification |
Storage Buffer |
PBS with 50% Glycerol,0.03% Proclin300,0.5% BSA,pH 7.3. |
Storage |
Store at -20℃. Avoid freeze/thaw cycles. |
Unit |
Piece |
Specification |
50ul 100ul |
Reactivity |
Human Mouse |
Application |
IHC |