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My CartReactivity：M6A,Mouse,Rat,Human
Application：ELISA,RIP,IHC,DB
Clone Type：Monoclonal antibody
Storage：Store at -20℃. Avoid freeze / thaw cycles.
Host：Mouse
Qty：
Size：
| Name | Anti-M6A Monoclonal Antibody |
| Host | Mouse |
| Clone Type | Monoclonal antibody |
| Subtype | IgG3 |
| Dilution Ratio | IHC 1:2000-8000. RIP 1:1000-4000. DB 1:1000-4000. ELISA 1:2000-20000. |
| Target | M6A |
| Background | m6A (N6-methyladenosine) is the most abundant internal modification in mammalian mRNA. This modification is installed by the m6A methyltransferases or termed writerssuch as METTL3 and METTL14, and can be reversed by demethylases that serve as erasers such as FTO and ALKBH5. The stability of m6A-modified mRNA is regulated by m6A reader protein YTHDFs, which recognizes m6A and reduces the stability of target transcripts. m6A modification and its regulatory proteins play critical roles in cancer pathogenesis and progression. m6A modification is also invovled in viruses life cycles, suggesting that drugs targets to m6A pathway could be used for antiviral thereapy. |
| Purification Method | Protein A purification |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage | Store at -20℃. Avoid freeze / thaw cycles. |
| Unit | Piece |
| Specification | 50ul 100ul |
| Reactivity | M6A Mouse Rat Human |
| Application | ELISA RIP DB IHC |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Immunohistochemistry of paraffin-embedded mouse testis using m6A antibody diluted at 1:4000.
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