Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
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Purity:≥95%
Appearance:Lyophilized powder
Storage:Store at -20℃,2 years.(Avoid freeze/thaw cycles)
Product Type | Peptides |
Sequence(1LC) | RKRRQ-pT-SM |
Sequence(3LC) | Arg-Lys-Arg-Arg-Gln-pThr-Ser-Met |
Molecular Formula | C41H80N19O15S1P1 |
Molecular Weight | 1142.24 |
Purity | ≥95% |
Appearance | Lyophilized powder |
Salt Form | Trifluoroacetate salt |
Source | Synthetic |
Storage | Store at -20℃,2 years.(Avoid freeze/thaw cycles) |
Category/Label | Other Peptides |
Background | This peptide, amino acids 140 to 147 fragment of p21, is phosphorylated on Thr145. Pim-1 can efficiently phosphorylate p21 on Thr145 in vitro. Pim-1 is a serine/threonine kinase involved in the transduction of cytokine-triggered mitogenic signals. When p21 is phosphorylated on Thr145, it localizes to the nucleus and causes the disruption of the association between proliferating cell nuclear antigen and p21. Phosphorylation of Thr145 promotes stabilization of p21. |
In Vitro | undetected |
Reference | [1] Zhang, Y. et al. Mol. Cancer Res. 5, 909 (2007); [2] Mochizuki, T. et al. J. Biol. Chem. 274, 18659 (1999). |
Unit | Bottle |
Specification | 1mg 5mg |