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My CartCAS：957792-67-5
Molecular Formula：C100H165N25O28S2
Molecular Weight：2229.68
Purity：≥95%
Appearance：Lyophilized powder
Storage：Store at -20℃，2 years.(Avoid freeze/thaw cycles)
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| Product Type | Peptides |
| CAS | 957792-67-5 |
| Sequence(1LC) | YSMKETTMKIIPFNRLSIG |
| Sequence(3LC) | Tyr-Ser-Met-Lys-Glu-Thr-Thr-Met-Lys-Ile-Ile-Pro-Phe-Asn-Arg-Leu-Ser-Ile-Gly |
| Molecular Formula | C100H165N25O28S2 |
| Molecular Weight | 2229.68 |
| Purity | ≥95% |
| Appearance | Lyophilized powder |
| Salt Form | Trifluoroacetate salt |
| Source | Synthetic |
| Storage | Store at -20℃，2 years.(Avoid freeze/thaw cycles) |
| Category/Label | Other Peptides |
| Background | This fibrinogen-derived inhibitory peptide attenuates microglia activation and suppresses relapsing paralysis in multiple sclerosis (MS). Fibrinogen is a regulator of microglia activation and interaction of fibrinogen with the microglia integrin receptor M1. Because blocking fibrinogen-M1 interactions affects the pro-inflammatory but not the pro-coagulant properties of fibrinogen, targeting this gamma-fibrinogen epitope could represent a potential therapeutic strategy for MS and other neuroinflammatory diseases associated with blood-brain barrier disruption and microglia activation. |
| Reference | [1] Adams, R. et al. J. Exp. Med. Published online 5 March 2007 doi:10.1084/jem.20061931. |
| Unit | Bottle |
| Specification | 1mg 5mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
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