{{cart_num}}
My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Ubiquitin > (2-chloro-N) - 3, 4-dimethoxybenzyl acetamideCAS：65836-72-8
Molecular Formula：C11H14ClNO3
Molecular Weight：243.69
Storage：Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥98%
Appearance：White to off-white Solid
Qty：
Size：
| CAS | 65836-72-8 |
| Name | (2-chloro-N) - 3, 4-dimethoxybenzyl acetamide |
| Molecular Formula | C11H14ClNO3 |
| Molecular Weight | 243.69 |
| Solubility | Soluble in DMSO ≥5mg/mL(Need ultrasonic) |
| Purity | ≥98% |
| Appearance | White to off-white Solid |
| Storage | Powder:2-8℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 604-604-1 |
| MDL | MFCD01733639 |
| SMILES | O=C(NCC1=CC=C(OC)C(OC)=C1)CCl |
| InChIKey | CETPWRGZGWGPSV-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H14ClNO3/c1-15-9-4-3-8(5-10(9)16-2)7-13-11(14)6-12/h3-5H,6-7H2,1-2H3,(H,13,14) |
| PubChem CID | 2392259 |
| Target Point | UBA5 |
| Passage | Ubiquitin |
| Background | (2-chloro-N)-3,4-dimethoxybenzyl acetamide is a selective inhibitor of ubiquitin-like modifier activating enzyme 5 (UBA5). |
| Biological Activity | DKM 2-93 is a relatively selective inhibitor of UBA5 with an IC50 of 430 μM.[1] |
| IC50 | IC50: 430μM(UBA5);90μM(PaCa2 cells);30μM(Panc1 cells)[1] |
| Data Literature Source | [1]. Roberts AM，et al. Chemoproteomic Screening of Covalent Ligands Reveals UBA5 As a Novel Pancreatic Cancer Target. ACS Chem Biol. 2017 Apr 21;12(4):899-904. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
Note：
1. The products are all for scientific research use only. Do not use it for medical, clinical diagnosis or treatment, food and cosmetics, etc. Do not store them in ordinary residential areas.
2. For your safety and health, please wear laboratory clothes, disposable gloves and masks.
3. The experimental results may be affected by many factors, after-sale service is limited to the product itself and does not involve other compensation.
Sorry, there is no more information.
Sorry, there is no more information.
Manual Download
