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My Cart> Small Molecule Compounds > Inhibitors & Antagonists & Agonists > Apoptosis > Deferoxamine MesylateCAS：138-14-7
Molecular Formula：C26H52N6O11S
Molecular Weight：656.79
Storage：Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year
Purity：≥92%
Appearance：White to off-white Solid
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| CAS | 138-14-7 |
| Name | Deferoxamine Mesylate |
| Molecular Formula | C26H52N6O11S |
| Molecular Weight | 656.79 |
| Solubility | Soluble in Water ≥20mg/mL |
| Purity | ≥92% |
| Appearance | White to off-white Solid |
| Storage | Powder:-20℃，2 years;Insolvent(Mother Liquid):-20℃，6 months;-80℃，1 year |
| EC | EINECS 205-314-3 |
| MDL | MFCD00058605 |
| SMILES | O=C(N(CCCCCN)O)CCC(NCCCCCN(C(CCC(NCCCCCN(C(C)=O)O)=O)=O)O)=O.CS(=O)(O)=O |
| InChIKey | IDDIJAWJANBQLJ-UHFFFAOYSA-N |
| InChI | InChI=1S/C25H48N6O8.CH4O3S/c1-21(32)29(37)18-9-3-6-16-27-22(33)12-14-25(36)31(39)20-10-4-7-17-28-23(34)11-13-24(35)30(38)19-8-2-5-15-26;1-5(2,3)4/h37-39H,2-20,26H2,1H3,(H,27,33)(H,28,34);1H3,(H,2,3,4) |
| PubChem CID | 62881 |
| Target Point | Amyloid-β;Ferroptosis |
| Passage | Neuronal Signaling |
| Background | Deferoxamine mesylate is the mesylate salt of Deferoxamine, an iron chelator. Deferoxamine is an inhibitor of ferroptosis. Deferoxamine reduces beta-amyloid (Aβ) deposition and induces autophagy. |
| Biological Activity | Deferoxamine mesylate (Ba 33112， Desferrioxamine B， DFOM， NSC 644468)是Deferoxamine的甲磺酸盐，它可形成铁络合物并用作螯合剂。Deferoxamine 是一种铁死亡的抑制剂，可在体外低氧和高血糖状态下稳定 HIF-1α 的表达并改善HIF-1α的活性。Deferoxamine 可降低 beta-amyloid (Aβ) 的沉积并诱导自噬。[1-3] |
| Data Literature Source | [1] Chuang Guo，et al. Front Aging Neurosci . 2015 Jun 2;7:104. [2] Xue Yao，et al. Neural Regen Res . 2019 Mar;14(3):532-541. [3] Li P，et al. Nat Immunol. 2021 Sep;22(9):1107-1117. |
| Unit | Bottle |
| Specification | 50mg |
Remark：These protocols are for reference only. Solarbio does not independently validate these methods.
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