Anti-FTO Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

FTO

Immunogen :

KLH conjugated synthetic peptide derived from human FTO

Synonym :

Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein;Fto;FTO_HUMAN;Protein fatso

Isotype :

IgG

Gene ID :

79068

Clone No :

Swiss Port :

Q9C0B1

Molecular weight :

58kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Dog Pig Cow Horse Rabbit Sheep

Application :

WB ELISA IHC-P IHC-F IF

Recommended dilution :

WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.