Anti-TIA1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TIA1

Immunogen :

Recombinant protein of human TIA1

Synonym :

Cytotoxic granule associated RNA binding protein 1;Cytotoxic granule associated RNA binding protein;mTIA-1;Nucleolysin TIA 1 isoform p40;Nucleolysin TIA-1 isoform p40;Nucleolysin TIA1 isoform p40;p40 TIA 1;p40-TIA-1 (containing p15-TIA-1);p40-TIA-1;RNA binding protein TIA 1;RNA binding protein TIA1;RNA-binding protein TIA-1;T-cell-restricted intracellular antigen-1;TIA 1;TIA 1 cytotoxic granule associated RNA binding protein;Tia;TIA-1;TIA1;TIA1 cytotoxic granule associated RNA binding protein;TIA1 cytotoxic granule associated RNA binding protein like 1;TIA1 protein;TIA1_HUMAN;TIAL1;TIAR;WDM;

Isotype :

IgG

Gene ID :

7072

Clone No :

Swiss Port :

P31483

Molecular weight :

24/42/43kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.