PRODUCT DESCRIPTION
Description :
Recombinant Mouse Chitinase-Like Protein 3 is produced by our Mammalian expression system and the target gene encoding Tyr22-Tyr398 is expressed with a 6His tag at the C-terminus.Formulation :
Lyophilized from a 0.2 米m filtered solution of PBS, pH7.4.Purity :
Greater than 95% as determined by reducing SDS-PAGE.Endotoxin :
Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.Reconstitution :
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 米g/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.Storage :
Lyophilized protein should be stored at < -20~C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7~C for 2-7 days.Aliquots of reconstituted samples are stable at < -20~C for 3 months.Background :
Chitinase 3-like 3 gene, also known as YM1 and ECF-L, encodes a precursor protein with 398 amino acid residues with a 21 residue signal sequence. Chitinase 3-like 3 protein is a lectin that binds saccharides with a free amino group, such as glucosamine or galactosamine. Binding to oligomeric saccharides is much stronger than binding to mono- or disaccharides. Also binds heparin and G1cN oligomers, and is produced primarily by macrophages during inflammation. It has chemotactic activity for T-lymphocytes, bone marrow cells and eosinophils.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data