Anti-TGFB1I1 Polyclonal Antibody

No :   K110260P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TGFB1I1

Immunogen :

A synthetic peptide of human TGFB1I1

Synonym :

ARA55;HIC-5;HIC5;TSC-5

Isotype :

IgG

Gene ID :

7041

Clone No :

Swiss Port :

O43294

Molecular weight :

49kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Predicted:Cow

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:100-300.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. May also regulate SLC6A3 and SLC6A4 targeting to the plasma membrane hence regulating their activity. In the nucleus, functions as a nuclear receptor coactivator regulating glucocorticoid, androgen, mineralocorticoid and progesterone receptor transcriptional activity. May play a role in the processes of cell growth, proliferation, migration, differentiation and senescence. May have a zinc-dependent DNA-binding activity.
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