Anti-DYRK1B Polyclonal Antibody

No :   K110262P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

DYRK1B

Immunogen :

A synthetic peptide of human DYRK1B

Synonym :

MIRK

Isotype :

IgG

Gene ID :

9149

Clone No :

Swiss Port :

Q9Y463

Molecular weight :

65/66/69kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Rat Predicted:Zebrafish Cow

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Cytoplasm

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Dual-specificity kinase which possesses both serine/threonine and tyrosine kinase activities. Enhances the transcriptional activity of TCF1/HNF1A and FOXO1. Inhibits epithelial cell migration. Mediates colon carcinoma cell survival in mitogen-poor environments. Inhibits the SHH and WNT1 pathways, thereby enhancing adipogenesis. In addition, promotes expression of the gluconeogenic enzyme glucose-6-phosphatase (G6PC).
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