Anti-SORBS2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SORBS2

Immunogen :

A synthetic peptide of human SORBS2

Synonym :

ARGBP2, KIAA0777

Isotype :

IgG

Gene ID :

8470

Clone No :

Swiss Port :

O94875

Molecular weight :

18/75/90/124/134kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Predicted:Zebrafish

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cytoplasm Cell membrane Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Adapter protein that plays a role in the assembling of signaling complexes, being a link between ABL kinases and actin cytoskeleton. Can form complex with ABL1 and CBL, thus promoting ubiquitination and degradation of ABL1. May play a role in the regulation of pancreatic cell adhesion, possibly by acting on WASF1 phosphorylation, enhancing phosphorylation by ABL1, as well as dephosphorylation by PTPN12 (PubMed:18559503). Isoform 6 increases water and sodium absorption in the intestine and gall-bladder.