Anti-RSPO1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

RSPO1

Immunogen :

A synthetic peptide of RSPO1

Synonym :

RSPO1;CRISTIN3;RSPO

Isotype :

IgG

Gene ID :

284654

Clone No :

Swiss Port :

Q2MKA7

Molecular weight :

22/26/29kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Secreted

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.