Anti-TLN1 Polyclonal Antibody

No :   K110282P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TLN1

Immunogen :

A synthetic peptide of TLN1

Synonym :

TLN1;ILWEQ;TLN;talin-1

Isotype :

IgG

Gene ID :

7094

Clone No :

Swiss Port :

Q9Y490

Molecular weight :

270kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cell membrane?Secreted

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells. The N-terminus of this protein contains elements for localization to cell-extracellular matrix junctions. The C-terminus contains binding sites for proteins such as beta-1-integrin, actin, and vinculin.
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