Anti-ARRB2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

ARRB2

Immunogen :

A synthetic peptide of ARRB2

Synonym :

ARRB2;ARB2;ARR2;BARR2

Isotype :

IgG

Gene ID :

409

Clone No :

Swiss Port :

P32121

Molecular weight :

44/46/47/48kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Predicted:Cow

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm Nucleus Cell membrane

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.