Anti-YWHAE Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

YWHAE

Immunogen :

A synthetic peptide of YWHAE

Synonym :

14-3-3E; HEL2; KCIP-1; MDCR; MDS; 14-3-3 protein epsilon

Isotype :

IgG

Gene ID :

7531

Clone No :

Swiss Port :

P62258

Molecular weight :

26/29kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC

Recommended dilution :

WB 1:2000-5000. IHC 1:50-200.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.