Anti-TNFAIP6 Polyclonal Antibody

No :   K110298P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNFAIP6

Immunogen :

A synthetic peptide of TNFAIP6

Synonym :

TNFAIP6; TSG-6; TSG6; TNF alpha induced protein 6

Isotype :

IgG

Gene ID :

7130

Clone No :

Swiss Port :

P98066

Molecular weight :

31kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Secreted

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.
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