PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
TNFAIP6Immunogen :
A synthetic peptide of TNFAIP6Synonym :
TNFAIP6; TSG-6; TSG6; TNF alpha induced protein 6Isotype :
IgGGene ID :
7130Clone No :
Swiss Port :
P98066Molecular weight :
31kDaPurification :
Octanoic acid-ammonium sulfate precipitationReactivity :
Human MouseApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
SecretedStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
The protein encoded by this gene is a secretory protein that contains a hyaluronan-binding domain, and thus is a member of the hyaluronan-binding protein family. The hyaluronan-binding domain is known to be involved in extracellular matrix stability and cell migration. This protein has been shown to form a stable complex with inter-alpha-inhibitor (I alpha I), and thus enhance the serine protease inhibitory activity of I alpha I, which is important in the protease network associated with inflammation. This gene can be induced by proinflammatory cytokines such as tumor necrosis factor alpha and interleukin-1. Enhanced levels of this protein are found in the synovial fluid of patients with osteoarthritis and rheumatoid arthritis.RELATED PRODUCTS
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REFERENCE LIBRARY
No data