PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
BIRC7Immunogen :
A synthetic peptide of BIRC7Synonym :
KIAP; LIVIN; ML-IAP; MLIAP; RNF50; baculoviral IAP repeat containing 7Isotype :
IgGGene ID :
79444Clone No :
Swiss Port :
Q96CA5Molecular weight :
32kDaPurification :
Affinity purificationReactivity :
HumanApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
Nucleus?CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variantsRELATED PRODUCTS
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REFERENCE LIBRARY
No data