PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
OGDHImmunogen :
Recombinant protein of human OGDHSynonym :
AKGDH;E1k;OGDCIsotype :
IgGGene ID :
4967Clone No :
Swiss Port :
Q02218Molecular weight :
48/116kDaPurification :
Affinity purificationReactivity :
Human MouseApplication :
WBRecommended dilution :
WB 1:1000-3000.Subcellular location :
Cytoplasm NucleusStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex, which mediates the decarboxylation of alpha-ketoglutarate. The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO2. The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data