Anti-NKIRAS2 Polyclonal Antibody

No :   K110398P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

NKIRAS2

Immunogen :

Recombinant protein of human NKIRAS2

Synonym :

KBRAS2

Isotype :

IgG

Gene ID :

28511

Clone No :

Swiss Port :

Q9NYR9

Molecular weight :

11/15/21kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Cytoplasm

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
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REFERENCE LIBRARY
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