PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
NKIRAS2Immunogen :
Recombinant protein of human NKIRAS2Synonym :
KBRAS2Isotype :
IgGGene ID :
28511Clone No :
Swiss Port :
Q9NYR9Molecular weight :
11/15/21kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WBRecommended dilution :
WB 1:1000-3000.Subcellular location :
CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data