PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
SCN9AImmunogen :
A synthetic peptide of human SCN9ASynonym :
ETHA; GEFSP7; hNE Na; hNE-Na; hNENa; NE NA; NENA; Neuroendocrine sodium channel; Peripheral sodium channel 1; PN1; Scn9a; SCN9A_HUMAN; Sodium channel protein type 9 subunit alpha; Sodium channel protein type IX subunit alpha; Sodium channel voltage gated type IX alpha; Sodium channel voltage gated type IX alpha polypeptide; Sodium channel voltage gated type IX alpha subunit; Voltage gated sodium channel alpha subunit Nav1.7; Voltage gated sodium channel subunit alpha Nav1; Voltage-gated sodium channel subunit alpha Nav1.7;Isotype :
IgGGene ID :
6335Clone No :
Swiss Port :
Q15858Molecular weight :
225/226kDaPurification :
Octanoic acid-ammonium sulfate precipitationReactivity :
Human Predicted:RabbitApplication :
IHCRecommended dilution :
IHC 1:100-300.Subcellular location :
Cell membrane CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient (PubMed:7720699, PubMed:17167479, PubMed:25240195, PubMed:26680203, PubMed:15385606, PubMed:16988069, PubMed:17145499, PubMed:19369487, PubMed:24311784). It is a tetrodotoxin-sensitive Na+ channel isoform (PubMed:7720699). Plays a role in pain mechanisms, especially in the development of inflammatory pain (PubMed:17167479, PubMed:17145499, PubMed:19369487, PubMed:24311784).RELATED PRODUCTS
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REFERENCE LIBRARY
No data