PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
CLN5Immunogen :
A synthetic peptide of human CLN5Synonym :
Ceroid lipofuscinosis neuronal 5; Ceroid-lipofuscinosis neuronal protein 5; CLN5; CLN5_HUMAN; NCL; Protein CLN5;Isotype :
IgGGene ID :
1203Clone No :
Swiss Port :
O75503Molecular weight :
41kDaPurification :
Affinity purificationReactivity :
Human Mouse Predicted:Cow Dog SheepApplication :
IHCRecommended dilution :
IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data