Anti-CLN5 Polyclonal Antibody

No :   K110424P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

CLN5

Immunogen :

A synthetic peptide of human CLN5

Synonym :

Ceroid lipofuscinosis neuronal 5; Ceroid-lipofuscinosis neuronal protein 5; CLN5; CLN5_HUMAN; NCL; Protein CLN5;

Isotype :

IgG

Gene ID :

1203

Clone No :

Swiss Port :

O75503

Molecular weight :

41kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Predicted:Cow Dog Sheep

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521).
RELATED PRODUCTS
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REFERENCE LIBRARY
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