PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
AZIN1Immunogen :
Recombinant protein of human AZIN1Synonym :
Antizyme inhibitor 1; AZI; Azin1; AZIN1_HUMAN; OAZI; OAZIN; ODC1L; Ornithine decarboxylase antizyme inhibitor;Isotype :
IgGGene ID :
51582Clone No :
Swiss Port :
O14977Molecular weight :
50kDaPurification :
Affinity purificationReactivity :
Human Mouse RatApplication :
WB IHCRecommended dilution :
WB 1:1000-3000. IHC 1:50-200.Subcellular location :
Nucleus CytoplasmStorage :
Store at -20~C. Avoid freeze / thaw cycles.Background :
Antizyme inhibitor (AZI) protein that positively regulates ornithine decarboxylase (ODC) activity and polyamine uptake. AZI is an enzymatically inactive ODC homolog that counteracts the negative effect of ODC antizymes (AZs) OAZ1, OAZ2 and OAZ3 on ODC activity by competing with ODC for antizyme-binding (PubMed:17900240, PubMed:26305948). Inhibits antizyme-dependent ODC degradation and releases ODC monomers from their inactive complex with antizymes, leading to formation of the catalytically active ODC homodimer and restoring polyamine production (PubMed:17900240).RELATED PRODUCTS
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REFERENCE LIBRARY
No data