Anti-PNKP Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PNKP

Immunogen :

Recombinant protein of human PNKP

Synonym :

Bifunctional polynucleotide phosphatase/kinase;DNA 5'-kinase/3'-phosphatase;Polynucleotide kinase-3'-phosphatase;Polynucleotide 3'-phosphatase ;2'(3')-polynucleotidase;Polynucleotide 5'-hydroxyl-kinase ;

Isotype :

IgG

Gene ID :

11284

Clone No :

Swiss Port :

Q96T60

Molecular weight :

53/57kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3'-phosphates from, or by phosphorylating 5'-hydroxyl groups on, the ribose sugar of the DNA backbone.