Anti-HSD3B7 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

HSD3B7

Immunogen :

Recombinant protein of human HSD3B7

Synonym :

CBAS1;PFIC4;SDR11E3;HSD3B7

Isotype :

IgG

Gene ID :

80270

Clone No :

Swiss Port :

Q9H2F3

Molecular weight :

21/41kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.