Anti-GPC3 Polyclonal Antibody

No :   K110673P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

GPC3

Immunogen :

A synthetic peptide of human GPC3

Synonym :

GPC3;DGSX;GTR2-2;MXR7;OCI-5;SDYS;SGB;SGBS;SGBS1;glypican-3

Isotype :

IgG

Gene ID :

2719

Clone No :

Swiss Port :

P51654

Molecular weight :

59/66/68kDa

Purification :

Affinity purification

Reactivity :

Human Predicted: Chimpanzee

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cell membrane Cytoplasm Nucleus Secreted

Storage :

Store at -20~C. Avoid freeze / thaw cycles.

Background :

Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
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