Anti-PTPN6 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PTPN6

Immunogen :

A synthetic peptide of human PTPN6

Synonym :

HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; SHP1; tyrosine-protein phosphatase non-receptor type 6

Isotype :

IgG

Gene ID :

821

Clone No :

Swiss Port :

P29350

Molecular weight :

638/67/70kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat Predicted: Chimpanzee Dog

Application :

IHC

Recommended dilution :

IHC 1:100-300.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.