Anti-PMS1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PMS1

Immunogen :

A synthetic peptide of human PMS1

Synonym :

PMS1;HNPCC3;MLH2;PMSL1;hPMS1

Isotype :

IgG

Gene ID :

5378

Clone No :

Swiss Port :

P54277

Molecular weight :

63/87/101/106kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

WB

Recommended dilution :

WB 1:1000-3000.

Subcellular location :

Nucleus

Storage :

Store at -20～C. Avoid freeze / thaw cycles.

Background :

This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.