Rat FABP1/L-FABP ELISA KIT

Species :

Rat

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

62.5pg/ml

Detection Range :

125-8000pg/ml

Assay Length :

2.5-3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Fatty Acid-Binding Protein 1

Synonyms :

FABP1; FABPL; fatty acid binding protein 1, liver; fatty acid-binding protein, liver; LFABP; L-FABP; L-FABPFatty acid-binding protein 1; Liver-type fatty acid-binding protein

Background :

Fatty Acid Binding Protein 1, also known as liver FABP, is a cytoplasmic transporter for long chain fatty acids, oxidized/peroxidized fatty acids, cholesterol, heme, Vitamin K, steroids, acyl CoA, leukotrienes, and prostaglandins. It is expressed by hepatocytes, simple columnar epithelium of the small intestine, and renal proximal tubule epithelium. FABP1 trafficks between the cytosol, peroxisomes, and nucleus. It delivers fatty acid cargo to the transcription factor PPAR alpha, leading to increased production of enzymes involved in the beta-oxidation of fatty acids. FABP1 also plays a role in the formation of prechylomicron vesicles by the endoplasmic reticulum.