Rat MIF Elisa Kit

Species :

Rat

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

15 pg/ml

Detection Range :

31.25-2000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum, plasma, Cell culture supernatant

Long Name :

macrophage migration inhibitory factor

Synonyms :

EC 5.3.2.1; EC 5.3.3.12; GIFmacrophage migration inhibitory factor; GLIF; Glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; macrophage migration inhibitory factor (glycosylation-inhibiting factor); MIF; MMIF; Phenylpyruvate tautomerase

Background :

MIF (macrophage migration inhibitory factor) is a pro-inflammatory cytokine that is released during microbial infection, ARDS, rheumatoid arthritis, atherosclerosis, type 2 diabetes, and cancer. It signals through CXCR4, CXCR7, or complexes of CD74-CD44. MIF exhibits potent paracrine and autocrine stimulatory effects on cell growth and survival and enhances the production of inflammatory cytokines. It also inhibits the effectiveness of immunosuppressive glucocorticoids.