Anti-PKM2 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

PKM2

Immunogen :

Recombinant fusion protein of human PKM2

Synonym :

CTHBP;HEL-S-30;OIP3;PK3;PKM2;TCB;THBP1;PKM

Isotype :

IgG

Gene ID :

P14618

Clone No :

Swiss Port :

P14618

Molecular weight :

60KDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB IHC IF

Recommended dilution :

WB 1:500-2000. IHC 1:50-200. IF 1:50-200.

Subcellular location :

Cytoplasm Nucleus

Storage :

Store at -20℃. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

Background :

This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported.