Anti-SHMT1 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SHMT1

Immunogen :

Recombinant protein of human SHMT1

Synonym :

SHMT1;CSHMT;SHMT

Isotype :

IgG

Gene ID :

6470

Clone No :

Swiss Port :

P34896

Molecular weight :

38/45/49/53kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Predicted:Bovine Orangutan Rabbit Sheep

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm Cell membrane

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.