PRODUCT DESCRIPTION
Conjugation :
UnconjugationHost :
RabbitClonality :
Polyclonal AntibodyGene symbol :
WSCD2Immunogen :
Recombinant protein of human WSCD2Synonym :
MGC117165;WSC domain containing 2Isotype :
IgGGene ID :
9671Clone No :
Swiss Port :
Q2TBF2Molecular weight :
64/66kDaPurification :
Octanoic acid-ammonium sulfate precipitationReactivity :
Human Mouse Predicted:ZebrafishApplication :
WB IHCRecommended dilution :
WB 1:1000-3000. IHC 1:50-200.Subcellular location :
CytoplasmStorage :
Store at -20℃. Avoid freeze / thaw cycles.Background :
Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.RELATED PRODUCTS
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REFERENCE LIBRARY
No data