Anti-WSCD2 Polyclonal Antibody

No :   K110995P
Size :   
Quantity :   
PRODUCT DESCRIPTION

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

WSCD2

Immunogen :

Recombinant protein of human WSCD2

Synonym :

MGC117165;WSC domain containing 2

Isotype :

IgG

Gene ID :

9671

Clone No :

Swiss Port :

Q2TBF2

Molecular weight :

64/66kDa

Purification :

Octanoic acid-ammonium sulfate precipitation

Reactivity :

Human Mouse Predicted:Zebrafish

Application :

WB IHC

Recommended dilution :

WB 1:1000-3000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

Uridine diphosphatase (UDPase) that promotes protein N-glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. The nucleotide hydrolyzing preference is GDP > IDP > UDP, but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling.
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