Anti-SPART Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SPART

Immunogen :

Recombinant protein of human SPART

Synonym :

SPARTIN;TAHCCP1;SPG20;spartin

Isotype :

IgG

Gene ID :

23111

Clone No :

Swiss Port :

Q8N0X7

Molecular weight :

73kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

WB IHC

Recommended dilution :

WB 1:2000-5000. IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). [provided by RefSeq, Nov 2008]