Anti-NLRP12 Polyclonal Antibody

Conjugation :

Unconjugation

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

NLRP12

Immunogen :

Recombinant protein of human NLRP12

Synonym :

NLRP12;CLR19.3;FCAS2;NALP12;PAN6;PYPAF7;RNO;RNO2

Isotype :

IgG

Gene ID :

91662

Clone No :

Swiss Port :

P59046

Molecular weight :

32/102/107/114/120kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm

Storage :

Store at -20℃. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.