Anti-SIRT3 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SIRT3

Immunogen :

Recombinant protein of human SIRT3

Synonym :

SIR2L3

Isotype :

IgG

Gene ID :

23410

Clone No :

Swiss Port :

Q9NTG7

Molecular weight :

44kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

IHC

Recommended dilution :

IHC 1:15-50.

Subcellular location :

Mitochondrion matrix

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.