Anti-SIRT2 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

SIRT2

Immunogen :

Recombinant protein of human SIRT2

Synonym :

SIR2;SIR2L;SIR2L2

Isotype :

IgG

Gene ID :

22933

Clone No :

Swiss Port :

Q8IXJ6

Molecular weight :

43kDa

Purification :

Affinity purification

Reactivity :

Human Mouse Rat

Application :

WB

Recommended dilution :

WB 1:200-1000.

Subcellular location :

Cell projection Chromosome Cytoplasm Midbody Myelin membrane Nucleus Perikaryon centriole centrosome cytoskeleton growth cone microtubule organizing center perinuclear region spindle

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Several transcript variants are resulted from alternative splicing of this gene.