Anti-TNF14 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

TNF14

Immunogen :

A synthetic peptide of human TNF14

Synonym :

Isotype :

IgG

Gene ID :

8740

Clone No :

Swiss Port :

O43557

Molecular weight :

22/26kDa

Purification :

Affinity purification

Reactivity :

Human Mouse

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

Cytoplasm Cell membrane

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.