Anti-NALP4 Polyclonal Antibody

Conjugation :

Unconjugate

Host :

Rabbit

Clonality :

Polyclonal Antibody

Gene symbol :

NALP4

Immunogen :

A synthetic peptide of human NALP4

Synonym :

CT58;PAN2;PYPAF4

Isotype :

IgG

Gene ID :

147945

Clone No :

Swiss Port :

Q96MN2

Molecular weight :

56/103/113kDa

Purification :

Affinity purification

Reactivity :

Human

Application :

IHC

Recommended dilution :

IHC 1:50-200.

Subcellular location :

/

Storage :

Store at -20°C. Avoid freeze / thaw cycles.

Background :

May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.