PRODUCT DESCRIPTION
Species :
HumanAssay Type :
Solid Phase Sandwich ELISASensitivity :
60 pg/mlDetection Range :
125-8,000 pg/mlAssay Length :
3.5hSample Type :
Serum; Plasma; Cell culture supernatant.Long Name :
Ribonuclease ASynonyms :
RNASE1; RAC1; RIB1; RNS1; Ribonuclease A family member 1, pancreatic; Ribonuclease pancreatic;Background :
This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3 -side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2 ,3 -cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.RELATED PRODUCTS
No data
REFERENCE LIBRARY
No data