Human RNase A/RNASE1 Elisa Kit

No :   SEKH-0385
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Human

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

60 pg/ml

Detection Range :

125-8,000 pg/ml

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant.

Long Name :

Ribonuclease A

Synonyms :

RNASE1; RAC1; RIB1; RNS1; Ribonuclease A family member 1, pancreatic; Ribonuclease pancreatic;

Background :

This gene encodes a member of the pancreatic-type of secretory ribonucleases, a subset of the ribonuclease A superfamily. The encoded endonuclease cleaves internal phosphodiester RNA bonds on the 3 -side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2 ,3 -cyclic nucleotides, with a pH optimum near 8.0. The encoded protein is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
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