Human C-Peptide Elisa Kit


Product Description

Species: Human
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 8 pg/mL
Detection Range: 15.6-1000 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: C-Peptide
Synonyms: C-P; C-Peptide; IDDM2; ILPR; Insulin C-Peptide; insulin; IRDN; MODY10; Proinsulin C-Peptide; proinsulin
Background: Insulin and the IGFs are members of the insulin family of molecules. IGF-I and II are structurally homologous to proinsulin, and can be thought of as taking the shape of an exaggerated, inverted letter G. Intrachain disulfide bonds link sections of the G. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 2554), a C-peptide (aa 5589), and a 21 aa A chain (aa 90110). Removal of the C-peptide by proteolysis enables the formation of mature Insulin, a disulfidelinked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes.
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REFERENCE LIBRARY

No:SEKH-0500
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