Mouse Insulin Elisa Kit

No :   SEKM-0141
Size :   
Quantity :   
PRODUCT DESCRIPTION

Species :

Mouse

Assay Type :

Solid Phase Sandwich ELISA

Sensitivity :

0.09 ng/mL

Detection Range :

0.17-5.5 ng/mL

Assay Length :

3.5h

Sample Type :

Serum; Plasma; Cell culture supernatant; Urine; Tissue.

Long Name :

Insulin

Synonyms :

IDDM; IDDM1; IDDM2; ILPR; INS; Insulin; IRDN; MODY10;

Background :

Insulin and the IGFs are members of the insulin family of molecules. IGF-I and II are structurally homologous to proinsulin, and can be thought of as taking the shape of an exaggerated, inverted letter G. Intrachain disulfide bonds link sections of the G. The single chain insulin propeptide consists of a 30 amino acid B chain (aa 2554), a C-peptide (aa 5589), and a 21 aa A chain (aa 90110). Removal of the C-peptide by proteolysis enables the formation of mature Insulin, a disulfidelinked heterodimer of the A and B chains. Circulating C-peptide levels are elevated in hyperinsulinism, obesity, and type II diabetes.
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REFERENCE LIBRARY
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