Mouse KIM-1/TIM-1/HAVCR Elisa Kit


Product Description

Species: Mouse
Assay Type: Solid Phase Sandwich ELISA
Sensitivity: 15 pg/ml
Detection Range: 31-2000 pg/ml
Assay Length: 3.5h
Sample Type: Serum; Plasma; Cell culture supernatant.
Long Name: T Cell Immunoglobulin Mucin-1
Synonyms: CD365; HAVCR1; HAVCR-1; KIM1; KIM-1; TIM1; TIM-1;
Background: TIM-1 (T cell immunoglobulin and mucin domain 1), also known as KIM-1 and HAVcr1, is expressed on many immune cell types and epithelial cells. It binds to phosphatidylserine (PS), LMIR5/CD300b, TIM-1 (homophilic), TIM-4, IgA, and the glycoproteins of a number of enveloped viruses. Its interaction with PS enables TIM-1 to mediate the phagocytosis and clearance of apoptotic cells. TIM-1 signaling costimulates T cell activation and enhances Th2 cytokine production. TIM-1 serves as a cellular entry receptor for hepatitis A virus, Ebolavirus and Marburgvirus. Polymorphisms are associated with susceptibility to atopy, autoimmunity, and severe hepatitis A virus infection in humans. A soluble form of TIM-1 is elevated in the urine during nephropathy.
Molecular formula:
Molecular weight:
Storage:
Assay:
Application:
Cas No.:


REFERENCE LIBRARY

No:SEKM-0147
Size: